Martin Steinhoff, MD, PhD
Professor in Residence
Department of Dermatology
Contact Information
1701 Divisadero Street, 3rd Floor, San Francisco, CA 94115
415.353.7800 phone
415.353.7870 fax
415.476.6978 administrative assistant
Training
- MD: University of Marburg, Marburg, Germany
- D. M. Sc.: University of Marburg, Marburg, Germany
- PhD: University of Muenster, Germany
Dr. Martin Steinhoff joined the UCSF Department of Dermatology in January 2009 after an illustrious early career in Germany. He has Board Certifications in Dermatology and Allergy from Germany. Since 2000 he has been a professor of Dermatology at The University of Muenster, rising from Assistant Professor to Full Professor in only 5 years. He is an established laboratory scientist who studies the substances that cause inflammation of the skin. As a clinician he has expertise in rosacea/acne, hives (Urticaria), itching (pruritus), psoriasis and atopic dermatitis/eczema. He has run university consultative clinics and a day care clinic for these conditions in Germany for almost a decade.
Clinical Specialties
- Pruritus
- Atopic dermatitis and eczema
- Rosacea/Acne
- Urticaria
Research Interests
- Neuroimmunology
- Neuromedicine
- Neurogenic inflammation
- G protein-coupled receptor biology
- Allergy/Atopy
- Fibrosis/Scleroderma
Publications
- Roosterman D, Cottrell GS, Padilla BE, Muller L, Eckman CB, Bunnett NW, Steinhoff M. Endothelin-converting enzyme 1 degrades neuropeptides in endosomes to control receptor recycling. Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11838-43. Epub 2007 Jun 25.
- Roosterman D, Goerge T, Schneider SW, Bunnett NW, Steinhoff M. Neuronal control of skin function: the skin as a neuroimmunoendocrine organ. Physiol Rev. 2006 Oct;86(4):1309-79.
- Steinhoff M, Buddenkotte J, Shpacovitch V, Rattenholl A, Moormann C, Vergnolle N, Luger TA, Hollenberg MD. Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response. Endocr Rev. 2005 Feb;26(1):1-43.
- Steinhoff M, Neisius U, Ikoma A, Fartasch M, Heyer G, Skov PS, Luger TA, Schmelz M. Proteinase-activated receptor-2 mediates itch: a novel pathway for pruritus in human skin. J Neurosci. 2003 Jul 16;23(15):6176-80.
- Steinhoff M, Vergnolle N, Young SH, Tognetto M, Amadesi S, Ennes HS, Trevisani M, Hollenberg MD, Wallace JL, Caughey GH, Mitchell SE, Williams LM, Geppetti P, Mayer EA, Bunnett NW. Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism. Nat Med. 2000 Feb;6(2):151-8.
- Ikoma A, Steinhoff M, Stander S, Yosipovitch G, Schmelz M. The neurobiology of itch. Nat Rev Neurosci. 2006 Jul;7(7):535-47.
- Feld M, Shpacovitch VM, Ehrhardt C, Kerkhoff C, Hollenberg MD, Vergnolle N, Ludwig S, Steinhoff M. Agonists of proteinase-activated receptor-2 enhance IFN-gamma-inducible effects on human monocytes: role in influenza A infection. J Immunol. 2008 May 15;180(10):6903-10.
- Paus R, Schmelz M, Biro T, Steinhoff M. Frontiers in pruritus research: scratching the brain for more effective itch therapy. J Clin Invest. 2006 May;116(5):1174-86.